Myeloma

myeloma. A tumor due to hyperplasia of the bone marrow.

Myeloma  is a very rare malignant tumor of bone. Such tumors always appear only in connection with bone, are usually multiple, and are of the same type as other lymphoid tumors.

The cells of such tumors resemble very closely the type of plasma cell. These cells are arranged in masses without an intercellular substance, and the tumors are closely allied to the malignant lymphomata. The cases are always associated with albuminuria.

Symptoms. The chief symptoms of malignant tumors are swelling and pain, both of which oftentimes are extreme. The swelling may be spherical or spindle shaped.

Extension  to the joints may not occur for a great length of time. In many cases X-ray examination is the most reliable method of detecting the character of the bony change.

Treatment  of all sarcomata is early and complete removal. This means in nearly all cases, amputation of the affected bone, and it is important that the amputation should be of the entire bone through the joint between the bone and the body, rather than amputation of the bone in continuity. The reason for this is, that even in sarcomata, which have not extended to the soft parts, very frequently there have occurred metastases of tumor-cells throughout the blood sinuses of the affected bone, often times at a distance of several inches from the site of the original primary tumor.